Sonata
® (Zaleplon)
belongs
to the class of drugs called hypnotics, and is used for the
short term treatment of sleep problems (insomnia). Hypnotics
should generally be limited to 7 to 10 days of use. Reevaluation
is recommended if hypnotics are taken for more than 2 to 3
weeks.
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Sonata ® is manufactured by Lundbeck
Limited.
Chemical Name
: Zaleplon
Important
Note
The following
information is intended to supplement, not substitute for, the expertise
and judgment of your physician, pharmacist or other healthcare professional.
It should not be construed to indicate that use of the drug is safe,
appropriate, or effective for you. Consult your healthcare professional
before using this drug.
Uses
This medication is used for the short-term treatment of sleep problems
(insomnia). Sonata (Zaleplon) belongs to a new group
of medicines that are used to help individuals who have difficulty
falling asleep. It selectively binds to a particular part of a receptor
in the brain called GABA receptors. This causes the release of a
chemical called GABA (gamma amino butyric acid). GABA is a major
inhibitory chemical in the brain which is responsible for causing
sleepiness and controlling anxiety and fits. By increasing GABA
release, Zaleplon therefore helps individuals to fall asleep,
as well as decreasing anxiety and relaxing the muscles.
How to Use
Take Sonata by mouth, immediately before bedtime or after
you have gone to bed and have difficulty sleeping, as directed by
your doctor. Do not take this medication with, or immediately after,
a high-fat or heavy meal. Sonata helps you fall asleep. To
minimize side effects while you are awake (e.g., dizziness or memory
trouble), take this medication when you are in bed and are able
to get at least four hours of sleep before you need to be active
again. Do not use Sonata for longer than ten days without
your doctor's approval. If your sleep problems continue, consult
with your doctor. Use this medication exactly as prescribed. Do
not increase your dose, take it more frequently or use it for a
longer period of time than prescribed because this drug can be habit-forming.
Also, if used for a longer period of time, do not stop using this
medication without your doctor's approval.
Side
Effects
Headache, drowsiness, nausea or stomach upset may occur. If any
of these effects persist or worsen, notify your doctor promptly.
Tell your doctor immediately if you have any of these serious side
effects: dizziness, weakness, loss of coordination, muscle joint
pain. Tell your doctor immediately if you have any of these unlikely
but serious side effects: mental/mood changes, persistent trouble
sleeping, memory problems, loss of appetite, tingling of the hands
or feet, rash, itching, tremors, eye/ear problems. Tell your doctor
immediately if you have any of these very unlikely but serious side
effects: fast/slow/irregular pulse, chest pain, trouble breathing,
blood in the stool, unusual thirst, change in amount of urine. If
you notice other effects not listed above, contact your doctor or
pharmacist.
Precautions
Tell your doctor your medical history, including: allergies, liver
disease, lung/breathing problems, mental/mood problems (e.g., depression),
alcohol use or drug dependence. Avoid alcohol, as it may aggravate
certain side effects of this drug (e.g., dizziness, drowsiness).
Use caution when performing tasks requiring alertness (e.g., driving).
You may have trouble sleeping the first few nights after you stop
using this medication. This problem usually goes away after one
or two nights. If sleep problems persist, consult with your doctor.
Use with caution in the elderly, as they may be more sensitive to
the effects of this medication. This medication should be used only
when clearly needed during pregnancy. Discuss the risks and benefits
with your doctor. This medication passes into breast milk. Because
of the potential risk to the infant, breast-feeding while using
this medication is not recommended. Consult your doctor before breast-
feeding.
Drug
Interactions
Tell your doctor of all prescription and nonprescription medication
you may use, especially of: rifamycin antibiotics (e.g., rifampin,
rifabutin), antidepressants (e.g., imipramine, amitriptyline), ulcer
medication (e.g., cimetidine). Also report any drugs causing drowsiness
such as: other medicines for sleep, sedatives, tranquilizers, anti-anxiety
drugs, narcotic pain relievers (e.g., codeine), psychiatric medications
(e.g., thioridazine), anti-seizure medications (e.g., phenytoin,
phenobarbital, carbamazepine), muscle relaxants, antihistamines
that cause drowsiness (e.g., diphenhydramine). Check all medicine
labels carefully, especially cough-and-cold preparations, since
many contain antihistamines (e.g., diphenhydramine). Consult your
pharmacist regarding safe use of these products. Do not start or
stop any medicine without doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison control center
or emergency room immediately. Symptoms of overdose may include
drowsiness; confusion; sluggishness; loss of coordination; slow,
shallow breathing; and loss of consciousness.
Notes
Do not share this medication with others.
Missed
Dose
Not applicable.
Storage
Store at room temperature between 68 and 77 degrees F (20 to 25
degrees C) away from light and moisture.
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