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Sildenafil prevents the destruction of an enzyme cGMP and allows cGMP to accumulate and persist longer.. The longer cGMP persists, the more prolonged the engorgement of the penis. Dapoxetine belongs to a class of medicines sildenafil citrate jelly 5 mg 30 sachets known as Selective Serotonin Reuptake Inhibitors (SSRI) which inhibits the uptake of serotonin in the neural cells. The mechanism of action of Tadalafil is the same as Viagra (Sildenafil) and works by blocking an enzyme called PDE 5 which helps the smooth muscles in the penis to relax, thereby increasing blood flow to the penis. For ejaculation to happen in men, sildenafil citrate a reflex has to be passed on to the brain via the sympathetic nervous system. The inhibition of Serotonin sildenafil citrate jelly 5 mg 10 sachets uptake inhibits the ejaculatory expulsion of reflex to the brain, thereby preventing premature ejaculation in men.


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