Celecoxib is an NSAID family pain medicine used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain... It also prevents transmission of pain signals by nerves to the brain. Tattoo Numb is a water based pain relief cream with a potent combination of Lidocaine, Prilocaine and Benzocaine Sumatriptan relieves migraines by stimulating serotonin receptors in the brain which cause the muscles surrounding the blood vessels in the tattoo numb brain to contract and narrow the blood vessels.