Tattoo Numb is a water based celecoxib pain relief cream with a potent combination of Lidocaine, Prilocaine and Benzocaine Sumatriptan relieves migraines by stimulating serotonin receptors in the brain which cause the muscles surrounding the blood vessels in the brain to contract and narrow the blood vessels.. It also prevents transmission of pain signals by nerves to the brain.. Celecoxib is an NSAID family pain medicine used to treat pain or inflammation caused by many conditions tattoo numb such as arthritis, ankylosing spondylitis, and menstrual pain.