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NAPROSYN ®

Naprosyn ® (Naproxen) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and swelling (inflammation). Naprosyn ® (Naproxen) works by blocking the enzyme in your body that makes prostaglandins.

It is also used to treat headaches, muscle aches, backaches, tendonitis, bursitis, dental pain, menstrual cramps, arthritis, or gout. Naprosyn may be used to reduce fever, or relieve minor aches and pain due to the common cold or flu.

Tramaden is a safe, non-prescription pain relief medicine.

 
Naprosyn ®
  Product Ships Rx Price Order
Naprosyn (Naproxen) 375mg 30 Tablets USA Free $94
Naprosyn (Naproxen) 375mg 60 Tablets USA Free $144
Naprosyn (Naproxen) 500mg 30 Tablets USA Free $109
Naprosyn (Naproxen) 500mg 60 Tablets USA Free $169
Naproxen (Generic Naprosyn) 375mg 30 Tablets USA Free $49
Naproxen (Generic Naprosyn) 375mg 60 Tablets USA Free $54
Naproxen (Generic Naprosyn) 500 MG 30 Tablets USA Free $49
Naproxen (Generic Naprosyn) 500 MG 60 Tablets USA Free $54
Naproxen 100 X Tab(s) 250mg Global Free $31.58
Naproxen 200 X Tab(s) 250mg Global Free $59.51
Naproxen 30 X Tab(s) 500mg Global Free $27.12
Naproxen 300 X Tab(s) 250mg Global Free $88.45
Naproxen 60 X Tab(s) 500mg Global Free $53.14
Naproxen 90 X Tab(s) 500mg Global Free $78.88



Naprosyn ® is manufactured by Roche.

Chemical Name : Naproxen

Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

Uses
Naprosyn ® (Naproxen) is an anti-inflammatory NSAID used for the management of mild to moderate pain, fever, and inflammation. They work by reducing the levels of prostaglandins, chemicals that are responsible for pain, fever and inflammation. Other members of this class include ibuprofen (Motrin), indomethacin (Indocin), nabumetone (Relafen) and several others.
Naproxen was approved by the FDA in December, 1991.


How to take this medication
Naprosyn (Naproxen) comes as a tablet to take by mouth. The usual adult dose is 250-500 mg twice daily using regular naproxen tablets. The usual dose for Naprosyn controlled release tablets is 750 to 1000 mg given once daily. Naprosyn (Naproxen) should be given with food to reduce upset stomach. Take Naprosyn (Naproxen) with a full glass of water and do not lie down for 30 minutes after taking Naprosyn (Naproxen).

Side Effects
The most common side effects from Naprosyn (Naproxen) are rash, ringing in the ears, headaches, dizziness, drowsiness, abdominal pain, nausea, diarrhea, constipation, heartburn, fluid retention and shortness of breath. Naprosyn (Naproxen) also may cause stomach and intestinal bleeding and ulcers. Sometimes, stomach ulceration and intestinal bleeding can occur without any abdominal pain. Black tarry stools, weakness, and dizziness upon standing may be the only signs of the bleeding. People who are allergic to other NSAIDs should not use Naprosyn (Naproxen).

Contact your Doctor immediately if you experience severe stomach pain, swelling of hands/feet, sudden or unexplained weight gain, ringing in the ears (tinnitus), vision changes, rapid/pounding heartbeat, easy bruising/bleeding, change in amount of urine, severe headache, very stiff neck, mental/mood changes, or persistent sore throat or fever. may infrequently cause serious (rarely fatal) bleeding from the stomach or intestines.

Precautions
In certain conditions (e.g., arthritis), it may take upto 2 weeks, taken regularly, for
Naprosyn (Naproxen) to work. Do not stop taking Naprosyn (Naproxen) without checking with your doctor. Naprosyn (Naproxen) may alter certain lab test results. Make sure laboratory personnel and your doctors know you use Naprosyn (Naproxen).

Naprosyn (Naproxen) may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Naprosyn (Naproxen). Use a sunscreen or protective clothing if you must be outside for a prolonged period. Do not take Naprosyn (Naproxen) if you ever had any unusual or allergic reaction to aspirin, ibuprofen, celecoxib, or any other medicine used to treat pain, fever, swelling, or arthritis. Daily use of alcohol and tobacco, especially when combined with Naprosyn (Naproxen), will increase your risk for stomach bleeding.

The elderly may be more sensitive to the effects of
Naprosyn (Naproxen), especially stomach bleeding and kidney effects.

If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Naprosyn (Naproxen) during pregnancy; Naprosyn (Naproxen) should only be used when clearly needed during the first 6 months of pregnancy. Naprosyn (Naproxen) is not recommended for use during the last 3 months of pregnancy due to its potential for fetal harm. Naprosyn (Naproxen) is excreted in breast milk. If you are or will be breast-feeding, check with your doctor of pharmacist to discuss the risks to your baby.

Drug Interactions
Naprosyn (Naproxen) may reduce the blood pressure lowering effects of blood pressure medications. This may occur because prostaglandins play a role in the regulation of blood pressure. Individuals taking oral blood thinners or anticoagulants (e.g., warfarin) should avoid Naprosyn (Naproxen) because it also thins the blood, and excessive blood thinning may lead to bleeding.

When Naprosyn (Naproxen) is used in combination with aminoglycosides (e.g., gentamicin) the blood levels of the aminoglycoside may increase, presumably because the elimination of aminoglycosides from the body is reduced. This may lead to more aminoglycoside-related side effects.
Naprosyn (Naproxen) may increase the blood levels of lithium (Eskalith) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity.

Naprosyn (Naproxen) can aggravate paranoid symptoms in patients with schizophrenia, and increase symptoms of mania in patients with manic-depressive disease. Cimetidine (Tagamet) can increase blood levels of Naprosyn (Naproxen) and its side effects. The sedative effect of the medication can possibly impair the mental and physical abilities required for driving or operating machinery.

Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately.The following symptoms indicate an overdose: dizziness; fainting; fast heartbeat.

Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take a double dose to make up for a missed one.

Storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.

 

 
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 Pain Information : Acute pain is the body's alarm system. It signals that something is wrong. It signals that you are in danger of injury or that the injured part needs to be protected and rested. Chronic pain serves no useful purpose and may cause disability and distress to sufferers and their families. Estimates of the number of people with chronic pain vary from 8% to 45% depending on severity and whether medical help is sought. Chronic pain is more common in women and in the elderly. Many types of chronic pain have been identified. However some people with chronic pain do not have a diagnosis from their doctor. The Pain Relief Foundation funds research into the causes and treatment of chronic pain. If you have a pain problem, which needs treatment you should contact your own doctor who can refer you to a pain clinic in your area. This site is for information only and cannot be treated as a substitute for the medical advice of your own doctor. The Pain Relief Foundation is not able to offer individual medical advice.

NO-Naprosyn ( Naproxen ) modulates inflammation, nociception and downregulates T cell response
Anti-inflammatory non steroidal drugs releasing NO (NO-NSAIDs) are a new class of anti-inflammatory drugs to which has been added an NO-releasing moiety. These compounds have been shown to retain the anti-inflammatory, analgesic and antipyretic activity of the parent compound but to be devoid of gastrointestinal (GI) toxicity. Results show that both Naprosyn ( Naproxen ) and NO-Naprosyn ( Naproxen ) reduce inflammation and nociception associated with arthritis. In addition NO-Naprosyn ( Naproxen ) interferes to a larger extent with cellular mechanism involved in T cell activation in rat adjuvant arthritis indicating that introduction of the NO moiety in the Naprosyn ( Naproxen ) structure increases the effect at the level of the immune system.

Treatment of Pain : Pain can occur for many reasons, and strike in a variety of locations. Back pain, disc pain, facet and nerve root pain, chronic headache pains and migraines are just a few of the problems that we can diagnose and treat: Acute and Chronic Back Pain Pelvic Pain Post-surgical Failed Back Syndrome Diabetic Neuropathy Disc Pain, Facet and Nerve Root Pain Atypical Facial Pain Complex Regional Pain Syndromes; RSD Herpetic and Post-Herpetic Neuralgia Chronic Headache Pain; Migraines Other painful conditions resulting from disease and injury

Influence of a non-steroid antirheumatic drug on serum and urinary zinc in healthy volunteers
The effects of a commonly used non-steroid anti-inflammatory drug (Naprosyn ( Naproxen )) on zinc metabolism was studied in healthy volunteers. A significant increase in the urinary zinc excretion rate was found during treatment with Naprosyn ( Naproxen ), with a mean increase in the order of 35%. At the end of the treatment period the urinary zinc excretion fell towards normal, and after withdrawal of Naprosyn ( Naproxen ) the urinary excretion rate became normal. The mechanism by which Naprosyn ( Naproxen ) induces hyperzincuria is not known.

 

 

 

 

 

02nd September 2010