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Cialis ® (Tadalafil) is the newest prescribed prescription for the condition known as ED (Erectile Dysfunction). Cialis ® allows the penis to become hard and stay harder longer. The mechanism of action is the same as Viagra ®. By blocking an enzyme called phosphodiesterase -5, or PDE-5, Tadalafil helps the smooth muscles in the penis to relax, which effectively increases blood flow.

 
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Cialis Daily USE 2.5 MG 30 Tablets USA Free $219
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Cialis ® is manufactured by Eli Lilly.

Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

Uses
Cialis is in a class of medications known as PDE-5 inhibitors, which are used to treat cases of male impotence. Cialis is a fairly new impotence drug and has only just come onto the market. The UK is the first country in the world to be able to offer Cialis to its residents.

How to take this medication
Take Cialis exactly as your doctor prescribes. Cialis comes in different doses (5 mg, 10 mg, and 20 mg). For most men, the recommended starting dose is 10 mg. Cialis should be taken no more than once a day. Some men can only take a low dose of Cialis because of medical conditions or medicines they take. Your doctor will prescribe the dose that is right for you.

Side Effects
The early tests seem to indicate that Cialis doesn't affect blood pressure as much as other Erectile Dysfunction drugs. The clinical trials showed that statistically there was no significant difference in cardiovascular side effects from the placebo.

Precautions
If you have kidney problems, your doctor may start you on a lower dose of Cialis. If you have kidney or liver problems or you are taking certain medications, your doctor may limit your highest dose of Cialis to 10 mg and may also limit you to one tablet in 48 hours (2 days) or one tablet in 72 hours (3 days).

Drug Interactions
Consult your doctor about all nonprescription and prescription medication you may use, especially any nitrate medications (e.g., nitroglycerin, isosorbide dinitrate), nitroprusside (any "nitric oxide donor" medicines), cimetidine, erythromycin, azole antifungals (e.g., itraconazole, ketoconazole), mibefradil, rifamycins (e.g., rifampin) or high blood pressure medicines.

Storage
Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom. Keep this and all medications out of the reach of children.

Notes
According to clinical studies data on Cialis(TM) (tadalafil), men with ED reported a statistically significant improvement in successful intercourse attempts at 24 and 36 hours after taking the drug, compared to placebo. Other new findings including a summary of cardiovascular safety data showed no increased incidence of cardiovascular events during clinical studies. In all studies, compared with placebo, use of Cialis demonstrated consistent and statistically significant improvement and the treatment effect did not diminish over time.

 


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Impotence And Depression Linked : Successful treatment of erectile dysfunction in depressed men can lead to marked improvement in depression. Depression and erectile dysfunction are highly prevalent and frequently coexisting conditions in middle-aged and elderly men. Erectile problems affect more than 30 million men in the United States alone, according to the American Foundation for Urologic Disease. Erectile dysfunction increases progressively with age and men with cardiovascular risk factors are particularly susceptible. A study has found a strong correlation between change in erectile dysfunction and change in depressive symptoms - did not determine whether the depression caused erectile dysfunction, or erectile dysfunction caused the depression. The study suggests that depression can be a consequence of erectile dysfunction in some men.

Erectile Dysfunction (Impotence or Impotency) : Erectile dysfunction (ED), also known as impotence, is the inability to achieve or sustain an erection for satisfactory sexual activity. Erectile dysfunction is different from other conditions that interfere with sexual intercourse, such as lack of sexual desire and problems with ejaculation and orgasm. Erectile dysfunction (ED, impotence) varies in severity; some men have a total inability to achieve an erection, others have an inconsistent ability to achieve an erection, and still others can sustain only brief erections. The variations in severity of erectile dysfunction make estimating its frequency difficult. Many men also are reluctant to discuss erectile dysfunction with their doctors, and thus the condition is under-diagnosed. Nevertheless, experts have estimated that erectile dysfunction affects 30 million men in the Untied States. Erection begins with sexual stimulation. Sexual stimulation can be tactile (for example, by touching the penis), or mental (for example, by having sexual fantasies). Sexual stimulation generates electrical impulses along the nerves going to the penis and causes the nerves to release nitric oxide, which in turn increases the production of cyclic GMP (cGMP) in the smooth muscle cells of the corpora cavernosa. The cGMP causes the smooth muscles of the corpora cavernosa to relax, and allow rapid blood flow into the penis. The in-coming blood fills the corpora cavernosa, making the penis expand. The pressure from the expanding penis compresses the veins (blood vessels that drain the blood out of the penis) in the tunica albuginea, helping to trap the blood in the corpora cavernosa, thereby sustaining erection. Erection is reversed when cGMP levels in the corpora cavernosa fall, causing the smooth muscles of the corpora cavernosa to contract, stopping the inflow of blood and opening veins that drain blood away from the penis. The levels of the cGMP in the corpora cavernosa fall because it is destroyed by an enzyme called phosphodiesterase type 5.

Impotence Can Be Symptom Of Serious Illness : Erectile dysfunction (impotence), is no longer the taboo topic it once was, perhaps due to Viagra, the first oral drug for this condition. Whilst new drugs like Viagra have raised awareness of impotence, it is important for men to understand that impotence may be a symptom of other illnesses. Impotence can be the first sign of serious illnesses including diabetes; high blood pressure; kidney, liver or hormonal disorders; or coronary artery disease. Men with concerns about impotence should ask their doctor about treatment options which include; Oral medications: As well as Viagra, a second medication was approved by the FDA in 2003 and another is expected to be available by the end of the year. Injected drugs: Men can inject drugs into the penis to enhance blood flow. Self-administered intraurethral therapy: This involves using a small applicator to insert a tiny pellet of medicine into the urethra. Vacuum devices: These devices are a hollow plastic tube which is placed over the penis and pumped to create a vacuum that pulls blood into the penis. Surgical options: These are usually considered if other treatments aren't working. Semirigid rods or inflatable devices may be surgically implanted.

What Is An Erection : The penis has three long tubes of cylindrical erectile tissue which , are connected together by fibrous tissue. Called corpora cavernosa these two identical sections run parallel along the sides of the penis with the third tube (corpus spongiosum) laying underneath. These three also surround the urethra the tube which transports either sperm or urine. All three masses are like sponges in that they contain large spaces between loose networks of tissue. When the penis is limp (doctors call this 'flaccid' or 'resting'), then the spaces collapse and the tissue is reduced (that's why it's smaller). However when you start to get an erection, blood flows into these spaces causing the penis to enlarge. Now in theory this happens because of physical or psychological stimulation, but try telling that to a teenage boy who gets one while slumbering through algebra! Anyway as blood enters there is also a temporary reduction in the rate and volume of blood leaving the penis. So as the arteries carrying blood to the penis dilate the veins leading away use funnel-shaped valves to restrict the outflow of blood. Then as the erectile tissue begins to enlarge additional pressure happens as the veins to be compressed against the surrounding tissue, which in turn further restricts the outflow of blood. Now during all this process the three tubes don't swell up by the same pressure. The underneath tube (remember it's called the corpus spongiosum) doesn't become as hard as the two main sections (corpora cavernosa), if it did this would crush the urethra making it impossible to ejaculate (no thanks)! When this process is over your penis is becoming soft again as the arteries relaxed and contract.

 

 

 

 

 

09th February 2010