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Cialis ® (Tadalafil) is the newest prescribed prescription for the condition known as ED (Erectile Dysfunction). Cialis ® allows the penis to become hard and stay harder longer. The mechanism of action is the same as Viagra ®. By blocking an enzyme called phosphodiesterase -5, or PDE-5, Tadalafil helps the smooth muscles in the penis to relax, which effectively increases blood flow.

 
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Cialis ® is manufactured by Eli Lilly.

Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

Uses
Cialis is in a class of medications known as PDE-5 inhibitors, which are used to treat cases of male impotence. Cialis is a fairly new impotence drug and has only just come onto the market. The UK is the first country in the world to be able to offer Cialis to its residents.

How to take this medication
Take Cialis exactly as your doctor prescribes. Cialis comes in different doses (5 mg, 10 mg, and 20 mg). For most men, the recommended starting dose is 10 mg. Cialis should be taken no more than once a day. Some men can only take a low dose of Cialis because of medical conditions or medicines they take. Your doctor will prescribe the dose that is right for you.

Side Effects
The early tests seem to indicate that Cialis doesn't affect blood pressure as much as other Erectile Dysfunction drugs. The clinical trials showed that statistically there was no significant difference in cardiovascular side effects from the placebo.

Precautions
If you have kidney problems, your doctor may start you on a lower dose of Cialis. If you have kidney or liver problems or you are taking certain medications, your doctor may limit your highest dose of Cialis to 10 mg and may also limit you to one tablet in 48 hours (2 days) or one tablet in 72 hours (3 days).

Drug Interactions
Consult your doctor about all nonprescription and prescription medication you may use, especially any nitrate medications (e.g., nitroglycerin, isosorbide dinitrate), nitroprusside (any "nitric oxide donor" medicines), cimetidine, erythromycin, azole antifungals (e.g., itraconazole, ketoconazole), mibefradil, rifamycins (e.g., rifampin) or high blood pressure medicines.

Storage
Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom. Keep this and all medications out of the reach of children.

Notes
According to clinical studies data on Cialis(TM) (tadalafil), men with ED reported a statistically significant improvement in successful intercourse attempts at 24 and 36 hours after taking the drug, compared to placebo. Other new findings including a summary of cardiovascular safety data showed no increased incidence of cardiovascular events during clinical studies. In all studies, compared with placebo, use of Cialis demonstrated consistent and statistically significant improvement and the treatment effect did not diminish over time.

 


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Impotence Can Be Symptom Of Serious Illness : Erectile dysfunction (impotence), is no longer the taboo topic it once was, perhaps due to Viagra, the first oral drug for this condition. Whilst new drugs like Viagra have raised awareness of impotence, it is important for men to understand that impotence may be a symptom of other illnesses. Impotence can be the first sign of serious illnesses including diabetes; high blood pressure; kidney, liver or hormonal disorders; or coronary artery disease. Men with concerns about impotence should ask their doctor about treatment options which include; Oral medications: As well as Viagra, a second medication was approved by the FDA in 2003 and another is expected to be available by the end of the year. Injected drugs: Men can inject drugs into the penis to enhance blood flow. Self-administered intraurethral therapy: This involves using a small applicator to insert a tiny pellet of medicine into the urethra. Vacuum devices: These devices are a hollow plastic tube which is placed over the penis and pumped to create a vacuum that pulls blood into the penis. Surgical options: These are usually considered if other treatments aren't working. Semirigid rods or inflatable devices may be surgically implanted.

Levitra vs Viagra : The new pill for erectivle dysfunction is called Levitra. Levitra's makers say a major plus is that it works quickly. In clinical trials, some men using Levitra achieved an erection in 16 minutes. Viagra's maker has responded with studies showing half of men taking Viagra were able to have sex within 20 minutes. The Food and Drug Administration approved Levitra (vardenafil), an oral medication to treat erectile dysfunction in men (impotence). This is the second oral product approved for the treatment of erectile dysfunction. (Sildenafil, better known as Viagra, was the first.) Erectile dysfunction affects millions of men in the United States. Levitra acts by relaxing muscles in the penis and blood vessels, allowing increased blood flow into the penis, which produces an erection. Sildenafil is used for the treatment of erectile dysfunction of either physical or psychological cause. It has been found to be effective in treating erectile dysfunction in men with coronary artery disease, diabetes mellitus, hypertension, depression, coronary artery bypass surgery, and men who are taking antidepressants and several classes of anti-hypertensives. Vardenafil (Levitra) was the second oral medicine approved by the United FDA in the US for the treatment of erectile dysfunction. Like sildenafil (Viagra), vardenafil (Levitra) inhibits PDE5 which destroys cGMP.

What Is An Erection : The penis has three long tubes of cylindrical erectile tissue which , are connected together by fibrous tissue. Called corpora cavernosa these two identical sections run parallel along the sides of the penis with the third tube (corpus spongiosum) laying underneath. These three also surround the urethra the tube which transports either sperm or urine. All three masses are like sponges in that they contain large spaces between loose networks of tissue. When the penis is limp (doctors call this 'flaccid' or 'resting'), then the spaces collapse and the tissue is reduced (that's why it's smaller). However when you start to get an erection, blood flows into these spaces causing the penis to enlarge. Now in theory this happens because of physical or psychological stimulation, but try telling that to a teenage boy who gets one while slumbering through algebra! Anyway as blood enters there is also a temporary reduction in the rate and volume of blood leaving the penis. So as the arteries carrying blood to the penis dilate the veins leading away use funnel-shaped valves to restrict the outflow of blood. Then as the erectile tissue begins to enlarge additional pressure happens as the veins to be compressed against the surrounding tissue, which in turn further restricts the outflow of blood. Now during all this process the three tubes don't swell up by the same pressure. The underneath tube (remember it's called the corpus spongiosum) doesn't become as hard as the two main sections (corpora cavernosa), if it did this would crush the urethra making it impossible to ejaculate (no thanks)! When this process is over your penis is becoming soft again as the arteries relaxed and contract.

Impotency causes and solutions : There are an estimated twenty million men in the United States who suffer from impotency at some time in their lives. Impotency is also known as Erectile Dysfunction, or ED for short. It is defined as the inability to achieve or sustain an erection of the penis in order to have sexual intercourse. It doesn't matter what age or race a man is, as impotency happens because of a number of reasons. The usual reasons a man many experience a bout of impotency may include mental stress, physical stress, excessive consumption of alcohol, excessive use of tobacco, fatigue, mental anguish concerning sexual performance, or depression. Another cause of temporary impotency can be a negative side effect from a prescribed medication which the man is currently taking. These types of impotency are usually temporary and end when the cause is found and remedied. If, however, the period of impotency extends beyond a reasonable length of time, a visit to the doctor or healthcare professional is needed. There are many more-serious physical causes of impotency which may include, but are not limited to--diabetes, kidney disease, and a hormonal imbalance. The patient's doctor or healthcare professional will undoubtedly ask some questions about a man's sexual history so that he can properly diagnose the cause of the problem. The patient may possibly be run through a complete medical examination which may include some simple tests. A change of a prescription medicine may be in order if that is found to be causing the impotency problem. Or, if a hormonal imbalance is found, medication can be prescribed in order to successfully treat this problem. There are a number of other medical remedies for men today who suffer from impotency which can be used to alleviate this aggravating problem, also. As for the physical causes of impotency, most men can help to significantly decrease the risk of suffering from this problem by avoiding excessive tobacco use, excessive amounts of alcohol, and abstaining from illegal drug use. Men should try to follow a healthy diet which consists of plenty of fresh fruits and vegetables, whole-grain bread products, and plenty of protein from sources such as lean red meat, milk, yogurt, and cheeses. Another important part of the problems of sexual impotency is the man having an open, honest communication with his spouse or sexual partner. Even though impotency can cause a deep effect on a man's ego, and cause him to have feelings of shame and embarrassment, communication is an essential factor in the healing process. Every man needs to effectively communicate these feelings to his spouse or sexual partner. This openness and honesty will not only enable the spouse or sexual partner to better understand the man's feelings, but it will also enable both the man and his spouse or sexual partner to understand what the problem is and why there is a lack of sexual intimacy existing between them. The man may choose to have his spouse or sexual partner with him when he visits the doctor's office. In conclusion, there can be many causes, both mental and physical, for male sexual impotency. But, a man does not need to suffer with this problem as there are many different medications as well as medical remedies available today to alleviate this problem.

 

 

 

 

 

14th March 2010