Darvocet A500; Darvocet-N (Darvocet, Wygesic.

These brands no longer are available in the U.S.) Propoxyphene is a strong narcotic pain-reliever and cough suppressant but is weaker than other narcotics such as morphine, codeine, and hydrocodone. For more information on acetaminophen, please see acetaminophen (Tylenol). Acetaminophen is a non-narcotic analgesic and antipyretic (fever reducer). Acetaminophen relieves pain by elevating the pain threshold. The FDA first approved propoxyphene/acetaminophen combinations in October 1972. The precise mechanism of action is not known but may involve stimulation of opioid receptors in the brain.

The combination of propoxyphene and acetaminophen achieves greater pain relief than either taken separately.

It reduces fever through its action on the heat-regulating center of the brain. Tablets should be stored at room temperature, 15 to 30 C (59 to 86 F). Propoxyphene increases pain tolerance and decreases discomfort, but the presence of pain is still apparent. In addition to pain reduction, propoxyphene also causes sedation and respiratory depression. Propoxyphene and acetaminophen BRAND NAMES.

Propoxyphene/acetaminophen 50/325, 65/650, 100/325, 100/500, and 100 mg/650 mg STORAGE.