It also has been shown to possess anti-inflammatory, pain-relieving, and tissue-healing properties that may help protect the health of the joints. In a recent study people with cirrhosis of the liver who took SAMe for two years had a 47% lower death rate and much less of a need for a liver transplant.

One advantage it has over other medications in treating depression is that it works more quickly, often within one week. Supplementing with SAMe has been demonstrated to be an effective treatment for depression in some recent studies. People who have coronary heart disease, cirrhosis of the liver, Alzheimer's disease, and depression usually have low levels of SAMe in their bodies and might want to be supplementing with SAMe. Supplementing with SAMe has shown promise for people suffering with osteoarthritis, reducing their levels of pain, stiffness, and swelling equal to drugs such as ibuprofen and naproxen. It may also be helpful in a variety of liver diseases including cirrhosis of the liver. Folic acid and vitamin B12 are necessary for. Some fibromyalia patients in studies have had reduced pain, depression and fatigue.

Are There Any Benefits to Supplementing With SAMe.