ALLOPURINOL (Generic Zyloprim ®) Allopurinol (Generic Zyloprim ®) is a hyperuricemic agent used in the treatment of many symptoms of gout, including acute attacks, tophi (collection of uric acid crystals in the tissues, especially around joints), joint destruction, and uric acid stones. Gout is a form of arthritis characterized by increased blood levels of uric acid. Allopurinol works by reducing uric acid production in the body, thus preventing crystals from forming. Allopurinol works by reducing uric acid production in the body, thus preventing crystals from forming.

 

	Allopurinol

Product	Dosage	Qty	Consult	Price	Order
Allopurinol	300 mg	30 Tabs	FREE
Allopurinol	300 mg	60 Tabs	FREE
Allopurinol	300 mg	90 Tabs	FREE

Zyloprim ® is manufactured by GlaxoSmithKline.

Chemical Name : Allopurinol

Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

Uses
Allopurinol is used to treat chronic gout and to keep the body from producing excessive amounts of uric acid, which could lead to or aggravate various medical problems. It is used to prevent gout attacks, not to treat them once they occur. Allopurinol is also used to manage the increased uric acid levels in the blood of people with certain cancers, such as leukemia. It is also prescribed to manage some types of kidney stones.

Allopurinol will not stop a gout attack that is already underway. However, when taken over a period of several months, this drug will begin to reduce your symptoms. It's important to keep taking it regularly, even if it seems to have no immediate effect.

The usual starting dose of Allopurinol is 100 milligrams once daily. Your doctor may increase your dose by 100 milligrams per day at 1-week intervals until desired results are attained. The average dose is 200 to 300 milligrams per day for mild gout and 400 to 600 milligrams daily for moderate to severe gout. The most Allopurinol you should take in a day is 800 milligrams.

How to take this medication
Take Allopurinol exactly as prescribed. Your doctor will probably start you on a low Allopurinol dosage, increasing it gradually each week until you reach the Allopurinol dosage that is best for you. A typical starting Zyloprim dose is one 100-milligram tablet per day. You may want to take Allopurinol immediately after a meal to minimize the risk of stomach irritation. You should avoid taking large doses of Vitamin C because of the increased possibility of kidney stone formation.

Side Effects
Side effects cannot be anticipated. Only your doctor can determine if it is safe for you to continue taking Allopurinol. A skin reaction, the most common side effect of Allopurinol, may occasionally become severe or even fatal, you should stop taking Allopurinol if you notice even the beginnings of a rash. Such a rash may be itchy or scaly or may make your skin peel off in sheets; it may be accompanied by chills and fever, aching joints, or jaundice.

You may experience acute attacks of gout more often in the early stages of Zyloprim therapy, even when normal uric acid levels have been attained. These attacks Allopurinol become shorter and less severe after several months of therapy. A kidney problem may turn a normal dose of Allopurinol into an overdose. If you have a kidney disease, or a condition such as diabetes or high blood pressure that may affect your kidneys, your doctor should prescribe Allopurinol cautiously and order periodic blood and urine tests to assess your kidney function.

Drug Interactions
If Allopurinol is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Allopurinol with the following: Amoxicillin (Amoxil, Trimox, Wymox), Ampicillin (Omnipen, Principen), Azathioprine (Imuran), Blood thinners such as Coumadin, Cyclosporine (Sandimmune, Neoral), Drugs for diabetes, such as Diabinese and Orinase, Mercaptopurine (Purinethol), Probenecid (Benemid, ColBENEMID), Sulfinpyrazone (Anturane), Theophylline (Theo-Dur, Sl,-Phyllin, and others), Thiazide diuretics such as HydroDIURIL, Diuril, and others, Vitamin C.

Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately.The following symptoms indicate an overdose: dizziness; fainting; fast heartbeat.

Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take a double dose to make up for a missed one.

Storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.

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