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Aldara ® (Imiquimod) is a topical cream used for the treatment of external genital and perianal warts.

 
Aldara ®
  Product Ships Rx Price Order
Aldara 5% 12 Sachets USA Free $249
Aldara 5% 24 Sachets USA Free $359
Aldara 5% 36 Sachets USA Free $529



Aldara ® is manufactured by 3M Pharmaceuticals.

Chemical Name : Imiquimod

Important Note
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

Uses

External genital and perianal warts are cause by a virus called Human Papilloma Virus. These wart-like growths are oftentimes referred to as condyloma acuminata. While Aldara itself has not been demonstrated to have any of its own antiviral activity, Aldara cream is an immune response modifier that stimulates the body's own immune response system and helps the body fight this virus. It may do this via the induction of cytokines like alpha-interferon. Alpha-interferon is a complex compound normally produced by the human body that does have potent antiviral activity.

In a large clinical trial 50% of patients had complete clearing of their warts. The mean time to complete wart clearing was 10 weeks.

Aldara cream can effectively clear genital warts as quickly as 4 weeks, although the average time to healing is 10 weeks and may take as long as 16 weeks. Results vary from person to person.

  How to use this medication

  • Wash hands and open a new packet of Aldara cream just before bedtime.
  • Apply a thin layer of cream on the wart(s).
  • Rub the cream in until it vanishes.
  • Discard the open packet and wash hands.
  • Leave the cream on the wart(s) for 6 to 10 hours.
  • After 6 to 10 hours, wash the area where Aldara cream was applied with mild soap and water.

When Should I Use Aldara Cream?
Typically, dosing is once a day, 3 days a week:

Monday, Wednesday, and Friday, or Tuesday, Thursday, and Saturday

Apply Aldara cream at bedtime, after bathing, so you do not wash off the cream. Treatment with Aldara cream should continue until the warts are completely gone, or up to 16 weeks.

Can I Have Sex While Using Aldara Cream?
Sexual contact should be avoided while the cream is on the skin. If you decide to have sexual relations, apply Aldara cream after - not before - sexual activity. If you have already applied the cream, it should be washed off before sexual activity. In addition, Aldara cream may weaken condoms and diaphragms; therefore the cream should not be left on during sexual activity. The effect of Aldara cream on the transmission of genital warts is unknown.

Side Effects
Aldara cream doesn't destroy healthy skin. Most people who use Aldara cream don't complain of pain. One of the most common side effects is redness. This may be a sign that your immune system is working. Other common side effects are peeling of the skin, itching, flaking, and swelling around the warts.

Important Additional Information
Because Aldara cream doesn't cure Human Papilloma Virus, the cause of genital and perianal warts, new warts may form during treatment.

Aldara cream may weaken condoms and diaphragms, so sexual contact should be avoided while the cream is on the skin.

How Aldara cream affects the spread of genital warts to a partner is not known.

A woman who is or becomes pregnant while using Aldara cream should notify her health care provider immediately.

Do not use Aldara to treat internal (inside the vagina or anus) warts.

Skin color changes to the application site have also been reported.

Do not cover warts with bandages or other closed dressings.

Avoid using overly large amounts of cream.

A thin layer that completely covers each wart is enough.

 


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 Shingles : Herpes zoster: Also called shingles, zona, and zoster. The culprit is the varicella-zoster virus. Primary infection with this virus causes chickenpox (varicella). At this time the virus infects nerves (namely, the dorsal root ganglia) where it remains latent (lies low) for years. It can then be reactivated to cause shingles with blisters over the distribution of the affected nerve accompanied by often intense pain and itching. Shingles is a skin rash caused by the same virus that causes chickenpox. The virus responsible for these conditions is called Varicella zoster. After an individual has chickenpox, this virus lives in the nerves and is never fully cleared from the body. Under certain circumstances, such as emotional stress, immune deficiency (from AIDS or chemotherapy) or with cancer, the virus re- activates causing shingles. In most cases, however, a cause for the reactivation of the virus is never found. The herpes virus that causes shingles and chicken pox is not the same as the herpes virus that causes genital herpes (which can be sexually transmitted) and herpes mouth sores. Shingles is medically termed Herpes zoster. Before a rash is visible, the patient may notice several days to a week of burning pain and sensitive skin. Shingles start as small blisters on a red base, with new blisters continuing to form for 3-5 days. The blisters follow the path of individual nerves that comes out of the spinal cord (called dermatomal pattern). The entire path of the nerve may be involved or there may be areas with blisters and areas without blisters. Generally, only one nerve level is involved. In a rare case, more than one nerve will be involved. Eventually, the blisters pop and the area starts to ooze. The area will then crust over and heal. The whole process may take 3-4 weeks from start to finish. On occasion, the pain will be present but the blisters may never appear. This can be a very confusing cause of local pain!

Recurrent Herpes : By far the most common manifestation of herpes infections -- what people usually mean when they speak of "herpes" or "cold sores" -- is a recurrence of the virus when it is reactivated from its latent sleep in the nerves below the skin. What this looks like depends on where the virus has been hibernating: Labial herpes: This is the familiar cold sore that appears on the lip margins (labial refers to the lip). When labial herpes reappears, it usually occurs at most a few millimeters away from its previous location(s). Herpetic whitlow: Sometimes, the herpes virus shows up on the fingertip. This is especially common in dental and medical workers who have to put their fingers inside people's mouths, despite the use of gloves. Wrestlers' herpes: This has the picturesque name, "herpes gladiatorum." Gladiators, or nowadays just plain wrestlers, can contract herpes from an opponent who is shedding the virus. This form of herpes can appear all over the body. Wrestlers differ from most other patients with herpes who only develop recurrences in one spot. The reason for this is that although the antibodies in the bloodstream do not prevent the herpes from returning, they do make it hard for the virus to get a foothold anywhere else on the body.

Fever Blisters A small sore situated on the face or in the mouth that causes pain, burning, or itching before bursting and crusting over. The favorite locations are on the lips, chin or cheeks and in the nostrils. Less frequented sites are the gums or roof of the mouth. Fever blisters are caused by herpes simplex virus type 1. It lies latent (dormant) in the body and is reawakened (reactivated) by factors such as stress, sunburn, or fever from a wide range of infectious diseases including colds. Recurrences are less common after age 35. Sunscreen (SPF 15 or more) on the lips prevents recurrences of herpes from sunburn. The virus is highly contagious when fever blisters are present. It is spread by kissing. Children become infected by contact with someone who has a fever blister and then they spread the virus by rubbing their cold sore and touching other children. A person with fever blisters should be careful not to touch the blisters and spread the virus to new sites, such as the eyes or genitals. There is no cure for fever blisters. Medications that can relieve some of the pain and discomfort include ointments that numb the blisters, antibiotics that control secondary bacterial infections, and ointments that soften the crests of the sores. Acyclovir, an antiviral drug, prevents the herpes simplex virus from multiplying and, in pill form, has been reported to reduce the symptoms and frequency of recurrence. Fever blisters have plagued people for thousands of years. In ancient Rome, an epidemic of fever blisters prompted Emperor Tiberius to ban kissing in public ceremonies. Today, fever blisters still occur in epidemic proportions. About 100 million episodes of recurrent fever blisters occur yearly in the United States alone. Fever blisters are also called cold sores, labial herpes (herpes labialis, in Latin) and febrile herpes (herpes febrilis, in Latin).

Treatment for Shingles : There are several effective treatments for shingles. Drugs that fight viruses (antivirals), such as acyclovir (Zovirax) or famciclovir (Famvir) can reduce the duration of the rash if started early (within 48 hours of the appearance of the rash). The addition of steroids may also limit the length of time that a patient has pain with shingles. However, the benefit of both of these drugs is limited. In addition to antiviral medication, pain medications may be needed for symptom control. The affected area should be kept covered and dry. However, bathing is permitted and the area can be cleansed with soap and water. An aluminum acetate solution (Burows or Domeboro's solution, available at your pharmacy) can be used to help dry up the blisters and oozing.

 

 

 

 

 

12th March 2010